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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80b2555dee5cb8157fc833111c350f8423999d166107432d58893d2e70267ded' 
  AND token = 'MDme0hQVAAq2+RTxzNOEB29PrlMpsKNdA2x/CgW8ks8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}