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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28fc5db13653a650f83f70c680c411b5faa1344dea4cea71de604dd0dbd0a7a3' 
  AND token = 'zeI3jAf+V/2Xdwv4Lrbcol43FHEbbQGUGnsktEFAwic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}