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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8edef6379f46ec92d3d5fd119dc540f011073398a63d7e6c8a4ee19fe8f56b72' 
  AND token = 'OCLHQH7tSyIgmbVW9krVAA+OIN5dcIqVFAOzF3Fs5eo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}