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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e58b7b2214ad6eec8516e1d5e72c2adb59cea828d78ac23f2155caaa48ce591b' 
  AND token = 'VtOOOmACa3nVrCbRqMolsS3AOwDXCeW50x0touz1oxA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}