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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f48ce9f1110354c90bb01d8fac7a0d87af5c7d940063116802b85fa97f4a9e2' 
  AND token = 'JO/xfSYe+UCXCcAe+v1pFYB10TmTA63z0R2KoV5/jTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}