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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54b9a85c768a41bafc0bdeb786f1ce7acaca07e19be68a30cbbd2cfc265a691a' 
  AND token = 'BZY3yHucq0tNhN+QyLBqynukmdYsWENCbEKhp8KnvI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}