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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23ab2b7ca000253394acd950b9cc87f3026bc86216fbb4ea365323dae64a0542' 
  AND token = '38NUj7V4oKn9W0V5+kRWA7MZRcs6vMDkAbrOlMXtl0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}