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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '175d2d5c9f7a8176a7eaa0c137e1f1c032f8d654a04519ea9c6c07a7b1c6ee16' 
  AND token = '2axkDMUPWxBRXD56tYI3d5ZaPx6SnKNruCZT3W+OTLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}