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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6f533485a0a8906217d1d74168d8d9c8dac4d1b6e572f711d989a884e7f3728' 
  AND token = 'H4PehUvTs5f+e/Ll5jrMEUT8pGwQDvwTMVvA+c1kkGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}