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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e86d36e6131c5940b716de3109eb553f46c6a593a351caf0320c90b5e1388c1f' 
  AND token = 'EK48x6SFQW6vYP+OQ/jVozSMaLAMsiWlC0B6qt4iNro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}