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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c8f52b5af93ca6cdac7b173f8da64b56c66249ae8c32601b12e96c55072fc1e' 
  AND token = 'GIWIczOBtILWexjlx/ivksYHq+Bo+NMhzbhBEMcM4/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}