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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4330f1f493e607ae82742105eb2c87b9f1d775237378f05be55ecadb9c0c5cb' 
  AND token = 'VedxnRqWlCyA/vijX4IW6B24v+JIYoPpkuLfiedx+W4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}