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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ec135e2d651388e8320987ae2a9f22c6702d0c432a62b951db1092379939f06' 
  AND token = 'SKU6szCxmY2rNNWXi/wQHgEQMLX96l258USP8eB04hM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}