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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7673f73e464a4e2fa3a7d644359ad2317738d8c1b065a9d488829295e7ed911' 
  AND token = 'oBcBUXLTfc1Imvchb7m8CfXACe+jIegUzvPsm3Qj8vE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}