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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fe1b0abf4a6c7d7a417b963e8e8a6f5552796e8d53cf0e04f621123fef17015' 
  AND token = 'e+R28MeTRyDnDLQLaM/yz0SoB8/BbUeR8He9n9y41O0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}