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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd895521b2ba3dc98434f3bde332c7f570229a0b5d1b965eb58a03931905aa6fd' 
  AND token = 'adSBHZS2VI3MNvHwRXrYi9GcibHvzJh4IHvtxYMWYUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}