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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f22f17925be04593e21815bb7f6544c7882b2a46ab04a83ec24aa7fa9655c0d' 
  AND token = 'dwZGeo1w1Xf/kENIcSFklyhLl8cb6WUnQf1kANU97BI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}