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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0eba0fb5657f183c9b89c50aabc9603520cb7a483bdfc00426c5a05493a40c9' 
  AND token = 'BwsOD8SULFv1dIL5GO5EXyo9ld0HCrovCo2mJf67xqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}