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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da63549e4b77fc8dc07f5d2d4d46536580d94f7f643a30e71120aeeed616716f' 
  AND token = 'kFzQACNTkrRU0vOtU7jdNjPbHWHTXnT2qklfxHOXF2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}