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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0e74be6517c212a35b27c0a28ec174055e60faab8200283a7c0a709594402ec' 
  AND token = 'pezQKrqxrV1UME9CtL+efWz1gnmNqPYwIKwO+u1nN84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}