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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '462e41c511eb9a360d04b29ccf827fb235154b45c8cb84c88bf3effedd7a4466' 
  AND token = 'mCVDkqT7Aq0CCiYDS9oFwDtGYF5SKh8sjl9Q9NExMss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}