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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fe5f6d748b619e72ae5705b728b7344af5fea9c268e851fad449757cf59a353' 
  AND token = 'fgXiazEErgT98k0Qq2RWnefGZgI+dQ0r5Tt7cLd0zoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}