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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8374150f5d5e60f5a0a03129a7739db4183c662df482c63a3d4017deaa7e41ed' 
  AND token = 'lGcGrRNgfooNs3mdOZGqR97IGvFMn5Ws0YYXvrG3+zo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}