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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44357f8d098de1fa7dd7ef8135a7369e58ec4169d44df7695cf40e14d6f8ea0b' 
  AND token = 'V9xECR6kCai/j3o2uR830c7pRP83U3LV8i/ElfX+Ddg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}