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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4979f2e7c069d4d8dfcc3284d54139034ebc5385fc7ae71f8edec36908101e0b' 
  AND token = '7Nq5Eq0GgedlvR6leo+hs16axYAtYtm+bZb/Ev0lnQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}