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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4526934072e627891d840e191307cdc519fa3859446dc03902be077b928c56db' 
  AND token = 'YRF7P4RLcS2NKwfz4RYEP+r7WX78GHA1qXpNb9xlfUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}