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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2194a3d50acdfe7e3c241725f64b5022872268f2f4202ab3c12edfed263cdd8' 
  AND token = 'QTDmAVnJ6YJDWV3VDNvjsQ2OwMGAzbmflRYwYcHT9iU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}