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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51b5de551149cf7370af9b995384c26c7f3b132093bbb97aeec3a72b7351f701' 
  AND token = 'oHo4p+t3T2jR5BPQgT4fdTxEkAC0n09nxLhzDdzzas0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}