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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '056866201e90c9f4be8167bc5a60057ba1fa21fe9d4951d49976133ee8cc9455' 
  AND token = 'PkChGSq6aEGHsk0zCdb+iyaWSYwm3lETqLbAJJ8eH/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}