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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c64b9a724842d29d2f21e32faa38e0aaf6d385eb66bceb93d9675edbfe7665b4' 
  AND token = 'tU2YJyLCDOeO1FS531I1+TYg3kjag58IncMsc+FeSMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}