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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc8bf03fd9a3e074cf42eea4dc468b541d015bcde822ada59bb2017922e3bb17' 
  AND token = 'VWlFp2UKSyC57sz00s3uk94tn8w94wdPKzGT9XjIOLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}