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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fea955ce882e536bb676a6cdaa2a173138f1a1795ab156a0a16c638c9f28c9c' 
  AND token = 'wQPdHvgHAT0k6lPlp9G2fJNUFjJYUnQPd8LDHXJ+unU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}