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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdb6f3bccdca2defbbc99e28d054643050777c893b729693eb82584156a9ad58' 
  AND token = '0PMoAewAf9ArotxmiiBSoO05wYZEbJWySVAkw6bW4zg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}