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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f52e8d3ccf7534521cf8cf4ced02f971ded5d1b105586ef893a953bfa7810935' 
  AND token = 'oPIgCWtCOxIVEMsnrE81bru3HAZTZo1aR12ufz/gOZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}