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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e8c73bd04da0ca4be44e38ea594196a245a737d348578bcc9bc8370465b5e94' 
  AND token = 'HgVfPfUPjlPrGN2U+lMb8f6i6wjoRSYBp0+iPsi5Q0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}