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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7a2d855a88544ce7a447871c9bea39991c28c6dac71126ccb0bd1b67834ff30' 
  AND token = 'boi0EwgK0jN2Dz8YW/2KwLCR0WLHgi1DHeZOwMZ2tfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}