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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '755d66007a6fac2aaccb83e76763b9e8edcb4d7734bc167c74b9c50ecbb2786a' 
  AND token = 'L18dDuI0OBqa8LhdM7gbPzt1UyXwCqd+OuvuaBdU3TA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}