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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29d1da288763ac4b13691205b1e5388cd023e174f5a40522f8872ca3f2b54e0c' 
  AND token = 'cSA2MvLUkf/92en1a+88c0HX4+x7B+WyoLvuedcoIN8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}