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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d8caabd1def63f38b4110b577a40ea9cd04b8a67569e9678f14dc00516b1f1f' 
  AND token = '4pK7ILz7Bj7yvBBkzA/5CkCr2vKcOvSOewuuO0xj8fQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}