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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7456220ce25641f8e256216d4d5a4949b5b0851a34fb4de47be609b2e0547005' 
  AND token = '+VsfySs4qDxCEuVaupXCi6XL6N0EfeEQZB6Jm4iyN1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}