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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29597a25a800876f79319b2380d029735dad4d54620bfe3dd1f31987e95f876e' 
  AND token = 'rewa33Td1g500aAeVX4JHFU5OSfS5vDkKdZcsypFn+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}