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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b9beb2738ba3bbd682f9fc5cb9c97c1145888b25c7d3e307e2c8852dd511b64' 
  AND token = 'LbwJTUKcPzIwnEC8a1R0nar4XrkkaBBLaCrUAuMVV4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}