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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e597e84537a5a6dd5948cbec91a6529c85fc7a7ceb197462fd74d6210265e8fc' 
  AND token = 'asbsg8LXHbBF2i5tcTvTjNp0BHlA+bclbj95mptSWr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}