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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c63b438570a3e7f1f4747e840839d3a0c1cc3866a88eb66c248b37d4f432e655' 
  AND token = 'MVe4cXjWwl4q46t2Ewn6Qxe10TvIaNbIlfS1/uvMuTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}