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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a3a1a88f939c3023727d4ddde41380bac80da2852037b4842765a07f4e8638e' 
  AND token = 'baS0ALZ1euN3ft3WIZwaBPja59gkxEL9zRB9c06YI3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}