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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad4e406dbd1f7c36b6c3a89951c7b1a7aeaf640eb27c63c666a3d1a5ea8722c9' 
  AND token = 'QbxFsTiEyNvzDmfRUBp6bzDqVp63JC5h7Afs79B+6PE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}