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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b23b4a4b1e1b4b318677bcdba556050bf1213c7c2a8e7cec27a67ef3321bce59' 
  AND token = 'w0xdcA0nQeiUOir2lsJRO3MA57a3nUq7cj7TSs53Tjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}