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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb6f49d2eacd5c8caabf70f983384ca5b02d2741010d4c25f221a791f477b9a7' 
  AND token = 'l9eHzI2uExv+R3GNyiZBq61X6NrUakVKyVzkmQ8ORmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}