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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5e8290fba65113bd512f0ae802955ed18effa2b0d7f4e22640ab242c9f6f068' 
  AND token = 'p4Q1t6ee5ySG21O21I9nZZjyw62FfjY1x7F7mp86G1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}