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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24b2165509b785d1a46758bcb4a4214164f0cdddd43c97e9c14fc361f1fe5dae' 
  AND token = 'O0WLGmaxjJzFk65muQZ0LMXH3FYaaXmrEl3Dl2cbyTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}